New Particle Design and Its Preparation of NFkB Decoy Oligodeoxynucleotide (NDON) Loaded PLGA Nanospheres for Gene Delivery
نویسندگان
چکیده
منابع مشابه
Preparation and characterization of PLGA nanospheres loaded with inactivated influenza virus, CpG-ODN and Quillaja saponin
Objective(s): The purpose of this study was preparation and evaluation of PLGA nanospheres containing the influenza virus and different adjuvants, Quillaja saponin (QS) and CpG-ODN. Materials and Methods: Nanospheres were prepared using the double emulsion-solvent evaporation method. The morphological and physicochemical properties were studied by scanning electron microscopy...
متن کاملPLGA Nanospheres Loaded with Autoclaved Leishmania Major (ALM) and CpG-ODN: Preparation and in vitro Characterization
Objective(s) Several antigens, adjuvants and delivery systems have been evaluated for induction of protective immune responses against Leishmaniasis, but most of them have been inefficient. In this study, PLGA nanospheres as antigen delivery system CpG-ODN as an immunoadjuvant for increasing the immune responses against Autoclaved Leishmania major (ALM) were prepared and characterized. Materi...
متن کامل[Development of gene delivery system using PLGA nanospheres].
The development of nonviral vectors for the efficient and safe delivery to cells has long been awaited to facilitate gene therapy. Recently, many nonviral vectors modified with cationic lipids, cationic polymers, etc. have been reported. However, those nonviral vectors with cationic materials require improved stability, longer duration of gene expression, and reduced cytotoxicity. We successful...
متن کاملPreparation and characterization of PLGA nanospheres loaded with inactivated influenza virus, CpG-ODN and Quillaja saponin
OBJECTIVES The purpose of this study was preparation and evaluation of PLGA nanospheres containing the influenza virus and different adjuvants, Quillaja saponin (QS) and CpG-ODN. MATERIALS AND METHODS Nanospheres were prepared using the double emulsion-solvent evaporation method. The morphological and physicochemical properties were studied by scanning electron microscopy (SEM), determination...
متن کاملpreparation and characterization of plga nanospheres loaded with inactivated influenza virus, cpg-odn and quillaja saponin
objective(s): the purpose of this study was preparation and evaluation of plga nanospheres containing the influenza virus and different adjuvants, quillaja saponin (qs) and cpg-odn. materials and methods: nanospheres were prepared using the double emulsion-solvent evaporation method. the morphological and physicochemical properties were studied by scanning electron microscopy (sem), determina...
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ژورنال
عنوان ژورنال: Journal of the Society of Powder Technology, Japan
سال: 2007
ISSN: 0386-6157,1883-7239
DOI: 10.4164/sptj.44.453